Principal Investigator: Nicole D. Urban, ScD, Fred Hutchinson Cancer Research Center

Executive Committee, the decision-making body of the SPORE:
Martin (Mac) Cheever, MD, Fred Hutchinson Cancer Research Center
Steve Collins, MD, Fred Hutchinson Cancer Research Center
Mary L. Disis, MD, University of Washington
Charles W. Drescher, MD, Fred Hutchinson Cancer Research Center
Beth Y. Karlan, MD, Cedars Sinai Medical Center
Nicole D. Urban, ScD, Fred Hutchinson Cancer Research Center

Nicole UrbanThe goal of the Leadership and Administration Core (“Leadership Core”) is to ensure that translational goals of the POCRC are met. Leadership Core investigators are responsible for ongoing evaluation of scientific and translational progress of all projects. This interdisciplinary group of scientists ensures that interactions within and between projects are productive and that resources are allocated appropriately to take maximum advantage of the most promising research opportunities. Leadership Core investigators ensure that the cores meet the needs of projects without redundancy or conflict. In addition, the Leadership Core is responsible for overall scientific leadership, including Inter-SPORE communication, coordination and collaborations, and coordination and integration of POCRC activities. An External Advisory Board and a Steering Committee work with the Leadership Core to ensure that the POCRC is attaining scientific and translational goals.

A Patient Advocacy Group, previously under the supervision of the Clinical Core, now falls under the Leadership Core. This group’s purpose is to advise core investigators from a patient’s perspective about issues pertaining to design and implementation of recruitment protocols and content of participant materials, and to work to ensure the research program meets the needs of both the patient and community physician. Including the Patient Advocate Group in the Leadership Core will lead to enhanced exposure and, in turn, impact the work being conducted throughout the ovarian SPORE. Patient advocate participation and membership on various Leadership Core committees further assures that the translational objectives of the POCRC are met and scientific objectives can ultimately be translated to patient care. Please feel free to contact us for more information on the Patient Advocacy Group.

The research proposed in the POCRC Ovarian SPORE is translational. Its success is therefore measured by the degree to which it produces useful interventions that have an impact on outcomes. The nature of the research requires that decisions be made all along the way about how the research should proceed. Drs. Urban, Collins, Disis, Drescher, Cheever, and Karlan serve as investigators in the Leadership Core and comprise the Executive Committee, the decision-making body of the SPORE. This interdisciplinary group of scientists represents all of the disciplines and projects that comprise the POCRC.

To address the needs of the projects and the cores, experts in ovarian cancer, translational research, early detection/screening, epidemiology, genomics, immunology, statistical methods, informatics, pathology, and patient advocacy have been identified and recruited to serve in the Leadership Core. They will serve on substantive committees as well as provide mentorship to POCRC investigators who are experts in their own fields but less acquainted with other disciplines that are critical to career development in ovarian cancer translational research and the success of this SPORE. Through an external advisory board and various POCRC committees and working groups, the Leadership Core will provide the following functions:

  • Provide overall management and coordination of the SPORE
  • Meet the scientific advisory needs of the individual research projects
  • Oversee, plan, and evaluate SPORE activities including inter-SPORE activities
  • Promote, oversee, and evaluate interaction of cores and projects
  • Encourage, select, and guide developmental projects
  • Provide mentoring and career development
  • Manage, distribute, and re-allocate SPORE funds and other resources as appropriate
  • Oversee IRB activity
  • Ensure that scientific objectives can ultimately be translated to patient care
  • Initiate new activities in response to important translational research opportunities

Other Research

Project 1
Project 2
Project 3
Project 4
Project 5
Clinical Core
Informatics Core
Specimen Core
Leadership Core